Immunoregulatory T-cell defects

R S Geha; F S Rosen

doi:10.1016/0167-5699(83)90034-8

Immunoregulatory T-cell defects

Immunol Today. 1983 Aug;4(8):233-6. doi: 10.1016/0167-5699(83)90034-8.

Authors

R S Geha¹, F S Rosen

Affiliation

¹ Divisions of Allergy and Immunology, The Children's Hospital, and the Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.

PMID: 25290118
DOI: 10.1016/0167-5699(83)90034-8

Abstract

In normal circumstances homeostatic balance is maintained between T-cell help and suppression. In this review Raif Geha and Fred Rosen discuss examples of human diseases which involve excess or deficiency of T-cell help or T-cell suppression - diseases which have contributed greatly to an understanding of how T cells regulate the human immune response.