Human neurons derived from induced pluripotent stem cells as a new platform for preclinical drug screening and development

JAMA Neurol. 2014 Dec;71(12):1475-6. doi: 10.1001/jamaneurol.2014.2802.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Amyloid Precursor Protein Secretases / antagonists & inhibitors*
  • Amyloid Precursor Protein Secretases / metabolism*
  • Amyloid beta-Peptides / metabolism*
  • Humans
  • Induced Pluripotent Stem Cells / cytology*
  • Neurons / metabolism*
  • Peptide Fragments / metabolism*
  • Presenilin-1 / genetics*

Substances

  • Amyloid beta-Peptides
  • PSEN1 protein, human
  • Peptide Fragments
  • Presenilin-1
  • amyloid beta-protein (1-42)
  • Amyloid Precursor Protein Secretases