Photopheresis long after the initiation of chronic graft versus host in a child

Vedat Uygun; Hayriye Daloglu; Gulsun Karasu; Akif Yeşilipek

doi:10.1016/j.transci.2014.08.016

Photopheresis long after the initiation of chronic graft versus host in a child

Transfus Apher Sci. 2014 Oct;51(2):172-4. doi: 10.1016/j.transci.2014.08.016. Epub 2014 Aug 27.

Authors

Vedat Uygun¹, Hayriye Daloglu², Gulsun Karasu³, Akif Yeşilipek²

Affiliations

¹ Bahcesehir University, School of Medicine, MedicalPark Antalya Hospital, Pediatric Hematology and BoneMarrow Transplantation Unit, Antalya, Turkey. Electronic address: vedat@akdeniz.edu.tr.
² Bahcesehir University, School of Medicine, MedicalPark Antalya Hospital, Pediatric Hematology and BoneMarrow Transplantation Unit, Antalya, Turkey.
³ Bahcesehir University, School of Medicine, MedicalPark Goztepe Hospital, Pediatric Hematology and Bone Marrow Transplantation Unit, Istanbul, Turkey.

PMID: 25217990
DOI: 10.1016/j.transci.2014.08.016

Abstract

Extracorporeal photopheresis (ECP) has been used widely in the treatment of steroid-refractory chronic graft versus host disease (cGVHD). Several reports have applied an 'early treatment' approach due to the better response rates compared with late treatment. However, herein, we report a hematopoetic stem cell transplantation performed in a thalassemia major patient presenting with severe cGVHD who applied to our center for ECP treatment nearly 12 years after the onset of cGVHD.

Keywords: Graft versus host disease; Thalassemia; Transplantation.

Publication types

Case Reports

MeSH terms

Allografts
Child, Preschool
Chronic Disease
Female
Graft vs Host Disease / etiology
Graft vs Host Disease / pathology
Graft vs Host Disease / therapy*
Hematopoietic Stem Cell Transplantation*
Humans
Photopheresis*
beta-Thalassemia / pathology
beta-Thalassemia / therapy*