Abstract
The Ag-La2O3 hybrid nanoparticles were prepared by loading Ag nanoparticles on the surface of the La2O3 nanorods. The synthesis was a one-step process where sodium borohydride was used as a reducing agent to convert silver ions into silver nanoparticles, which were further deposited on the La2O3 nanorods. Moreover, they were found evenly dispersed upon the surface of La2O3 supports. The as-prepared Ag-La2O3 nanocomposites showed anti-oxidizing and significant antibacterial effect in vitro. Using the results from transmission electron microscope (TEM), the plausible mechanism was also proposed to explain the inhibition of bacterial growth. The present strategy can be potentially extended to develop drug-labels and other antibacterial agents.
Keywords:
Anti-oxide; Antibacterial effect; La2O3 nanorods; Mechanism; Silver nanoparticles.
Copyright © 2014 Elsevier Inc. All rights reserved.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Ammonium Hydroxide / chemistry
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Anti-Bacterial Agents / chemical synthesis
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Anti-Bacterial Agents / pharmacology*
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Antioxidants / chemical synthesis
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Antioxidants / pharmacology*
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Borohydrides / chemistry
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Cell Membrane / drug effects*
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Cell Membrane / ultrastructure
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Escherichia coli / drug effects*
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Escherichia coli / growth & development
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Escherichia coli / ultrastructure
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Gold / chemistry
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Lanthanum / chemistry
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Metal Nanoparticles / chemistry*
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Microbial Sensitivity Tests
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Microbial Viability / drug effects
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Microscopy, Electron, Transmission
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Nanocomposites / chemistry
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Particle Size
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Silver Nitrate / chemistry
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / growth & development
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Staphylococcus aureus / ultrastructure
Substances
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Anti-Bacterial Agents
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Antioxidants
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Borohydrides
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lanthanide nitrate
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Ammonium Hydroxide
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Lanthanum
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Gold
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sodium borohydride
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Silver Nitrate