The HIV care cascade and antiretroviral therapy in female sex workers: implications for HIV prevention

Expert Rev Anti Infect Ther. 2014 Oct;12(10):1203-19. doi: 10.1586/14787210.2014.948422. Epub 2014 Aug 30.

Abstract

To achieve viral suppression and fully benefit from antiretroviral therapy (ART), it is important that individuals with HIV know that they are HIV infected, link to and remain in HIV care, start and remain on ART and adhere to treatment. In HIV epidemics where female sex workers (FSWs) are key drivers of HIV transmission, the extent to which FSWs use ART and engage in the HIV care cascade could have a considerable impact on HIV transmission from FSWs to the wider population. In this article we review the spectrum of FSW engagement in the HIV care cascade, look at the impact of the HIV care cascade and ART use among FSWs on population-level HIV transmission and discuss HIV prevention for FSWs in the context of ART and the HIV care cascade.

Keywords: HIV care cascade; antiretroviral therapy; female sex worker; mathematical modeling; review.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-HIV Agents / therapeutic use*
  • Female
  • HIV Infections / diagnosis
  • HIV Infections / drug therapy
  • HIV Infections / prevention & control*
  • HIV Infections / transmission
  • Humans
  • Models, Theoretical
  • Patient Compliance
  • Sex Workers*

Substances

  • Anti-HIV Agents