Effects of a pre-existing food allergy on the oral introduction of food proteins: findings from a murine model

M Kulis; A W Burks

doi:10.1111/all.12519

Effects of a pre-existing food allergy on the oral introduction of food proteins: findings from a murine model

Allergy. 2015 Jan;70(1):120-3. doi: 10.1111/all.12519. Epub 2014 Nov 28.

Authors

M Kulis¹, A W Burks

Affiliation

¹ Department of Pediatrics, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

PMID: 25155558
DOI: 10.1111/all.12519

Abstract

Cashew-allergic mice develop elevated walnut-specific IgE upon oral feeding of walnut proteins. Ingestion of tree nuts in the presence of a known nut allergy could lead to additional sensitizations and anaphylaxis following subsequent exposure.

Keywords: cashew; egg; food allergy; peanut; walnut.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Allergens / immunology*
Animals
Antibody Specificity / immunology
Disease Models, Animal
Female
Food Hypersensitivity / diagnosis
Food Hypersensitivity / immunology*
Immunoglobulin E / immunology
Juglans / adverse effects
Mice
Plant Proteins / immunology*

Substances

Allergens
Plant Proteins
Immunoglobulin E