Abstract
T lymphocyte proliferation and differentiation are controlled by signaling pathways initiated by the T cell antigen receptor. Here we explore how key serine-threonine kinases and their substrates mediate T cell signaling and coordinate T cell metabolism to meet the metabolic demands of participating in an immune response.
MeSH terms
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Cell Differentiation / immunology*
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Cell Proliferation / physiology*
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Humans
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Lymphocyte Activation / immunology
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Protein Serine-Threonine Kinases / immunology*
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Receptors, Antigen, T-Cell / immunology*
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Signal Transduction / immunology*
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T-Lymphocytes / immunology*
Substances
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Receptors, Antigen, T-Cell
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Protein Serine-Threonine Kinases