Objective: To investigate the clinical feature, diagnose and therapeutic methods of paraglottic space primary paraganglioma.
Method: One case of paraglottic space primary paraganglioma was reported and the relevant literatures were reviewed.
Result: One case showed a hoarse voice, who was cured after the surgery of neck incision. NSE and CgA were positively expressed.
Conclusion: Paraganglioma of the paraglottic space is very rare. The diagnosis of paraglottic space primary paraganglioma bases on histopathology and immunohistochemistry. The immunohistochemistry and clinical character must be comprehensively analyzed to increase the diagnosis accuracy.