Epigenetics refers to functional alterations in gene expression or phenotype without any change of the underlying DNA sequence. It is the study of the potential of a cell or organism to express different traits through functional regulation of its gene transcription. Though it is met as a necessary process in biology, epigenetics may often play a crucial part in the development of specific pathologic conditions, including cardiovascular diseases and hypertension.
Keywords: DNA methylation; Epigenetics; Histone modification; Hypertension; nc-RNAs.
Copyright © 2014 Elsevier Inc. All rights reserved.