Diaminoglyoxime as a versatile reagent in the synthesis of bis(1,2,4-oxadiazoles), 1,2,4-oxadiazolyl-quinazolines and 1,2,4-oxadiazolyl-benzothiazinones

Rahim Hosseinzadeh Khanmiri; Abolghasem Moghimi; Ahmad Shaabani; Hassan Valizadeh; Seik Weng Ng

doi:10.1007/s11030-014-9536-4

Diaminoglyoxime as a versatile reagent in the synthesis of bis(1,2,4-oxadiazoles), 1,2,4-oxadiazolyl-quinazolines and 1,2,4-oxadiazolyl-benzothiazinones

Mol Divers. 2014 Nov;18(4):769-76. doi: 10.1007/s11030-014-9536-4. Epub 2014 Aug 13.

Authors

Rahim Hosseinzadeh Khanmiri¹, Abolghasem Moghimi, Ahmad Shaabani, Hassan Valizadeh, Seik Weng Ng

Affiliation

¹ Department of Chemistry, Faculty of Science, Imam Hossein University, Tehran, Iran.

PMID: 25115630
DOI: 10.1007/s11030-014-9536-4

Abstract

The synthesis of bis(1,2,4-oxadiazoles), 1,2,4-oxadiazolyl-quinazolines, and 1,2,4-oxadiazolyl-benzothiazinones has been investigated by the reaction of diaminoglyoxime with various ketones and methyl 2-aminobenzoate, 2-amino-5-chlorophenyl)(phenyl)methanone, and 2-mercapto benzoic acid in acetic acid either a catalyst or solvent at 100 °C.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Chemistry Techniques, Synthetic
Models, Molecular
Molecular Structure
Oxadiazoles / chemical synthesis*
Oximes / chemistry*
Quinazolines / chemical synthesis*

Substances

Oxadiazoles
Oximes
Quinazolines
diaminoglyoxime