Post hepatectomy liver failure: concept of management

J Gastrointest Cancer. 2014 Dec;45(4):405-13. doi: 10.1007/s12029-014-9646-3.

Abstract

Background: In literature, the reported mortality of posthepatectomy liver failure is <5 % and morbidity is 15-30 %. Around 3-8 % of patients develop liver failure after major hepatic resection.

Objective: The objective of the study was to provide current definitions and managing posthepatectomy liver failure (PHLF) as per severity and ISGLS grading.

Method: A systemic search of pubmed indexed articles was done and relevant articles were selected to formulate latest guidelines for PHLF.

Conclusion: We were able to make an algorithm for standardizing management so as to identify and treat PHLF as early as possible.

Publication types

  • Review

MeSH terms

  • Hepatectomy / adverse effects*
  • Humans
  • Liver Failure / etiology*
  • Liver Failure / pathology
  • Liver Failure / physiopathology
  • Postoperative Complications / physiopathology
  • Risk Factors