[Blood viscosity in patients with ischemic heart disease]

Kardiologiia. 2014;54(3):9-14. doi: 10.18565/cardio.2014.3.9-14.
[Article in Russian]

Abstract

Aim: To elucidate relation of blood viscosity to development of a hypoxic state of microcirculation in patients with ischemic heart disease (IHD).

Material and methods: We examined 42 patients with postmyocardial infarction cardiosclerosis and 30 healthy persons (control group). Measurements were made by rotatory viscometer at shear rates 1 - 10 s(-1).

Results: In patients with IHD we found increased blood viscosity and lowering of blood fluidity limit. Pathogenesis of increased blood viscosity in patients with IHD involves elevated blood fibrinogen, enhanced aggregation ability of erythrocytes, and accelerated formation of fine and large erythrocyte aggregates.

MeSH terms

  • Blood Viscosity*
  • Erythrocyte Aggregation*
  • Female
  • Fibrinogen / analysis
  • Hematocrit / methods
  • Humans
  • Hypoxia* / blood
  • Hypoxia* / etiology
  • Male
  • Microcirculation*
  • Middle Aged
  • Myocardial Ischemia* / blood
  • Myocardial Ischemia* / complications
  • Statistics as Topic

Substances

  • Fibrinogen