Excellent outcomes with expanded criteria donor kidneys: the role of the recipient's age

Clin Transpl. 2013:85-91.

Abstract

At the present time, the number of deceased donor kidney transplants performed annually has remained unchanged for 4 years. Desire for standard criteria donor (SCD) kidneys by recipients, coupled with high discard rates of donor kidneys, contributes to a lack of procedures being performed. A subgroup of recipients, those under age 50, may fare as well with an expanded criteria donor (ECD) allograft as those who receive an SCD kidney. The use of ECD allografts in recipients over 50 years of age, while projected to have poorer allograft survival than that produced with an SCD graft, still results in better recipient survival than patients who have elected to remain on dialysis.

MeSH terms

  • Adult
  • Aged
  • Cadaver
  • Delayed Graft Function / mortality*
  • Female
  • Graft Rejection / drug therapy
  • Graft Rejection / mortality*
  • Graft Survival
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Kidney Failure, Chronic / mortality*
  • Kidney Failure, Chronic / surgery
  • Kidney Transplantation / mortality*
  • Male
  • Middle Aged
  • Retrospective Studies
  • Tissue Donors / statistics & numerical data*
  • Treatment Outcome

Substances

  • Immunosuppressive Agents