Routine one-stage exchange for chronic infection after total hip replacement

Int Orthop. 2014 Dec;38(12):2477-81. doi: 10.1007/s00264-014-2466-z. Epub 2014 Jul 31.

Abstract

Purpose: We hypothesized that a routine one-stage exchange for treatment of chronically infected total hip replacement (THR) will lead to (1) a higher rate of infection recurrence and (2) a poorer hip outcome than the published rates after two-stage exchange.

Methods: Sixty-five cases have been treated consecutively with one-stage exchange. All patients have been followed for a period of three to six years or until death or infection recurrence.

Results: The five-year rate for infection recurrence was 16%. The five-year survival rate for recurrence of the index infection was 8%. Forty-two percent of the hips had a good or excellent PMA score, and 46% a good or excellent OH score.

Conclusions: Routine one-stage exchange was not associated with a higher recurrence rate and a poorer hip function than previously published series of two-stage exchange. Therefore, there is little support to choose two-stage exchange as the routine treatment for management of chronically infected THR.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Arthroplasty, Replacement, Hip / adverse effects*
  • Chronic Disease
  • Female
  • Follow-Up Studies
  • Hip Joint / microbiology
  • Hip Joint / surgery*
  • Hip Prosthesis / adverse effects
  • Humans
  • Male
  • Middle Aged
  • Prosthesis-Related Infections / etiology
  • Prosthesis-Related Infections / surgery*
  • Recurrence
  • Retrospective Studies
  • Survival Rate
  • Wound Healing

Substances

  • Anti-Bacterial Agents