Prevalence of EBV genotypes in Polish, Taiwanese and Arabic healthy students and association between genotypes and 30-bp deletion in the LMP-1 gene phylogenetic analysis

Pol J Microbiol. 2014;63(1):105-9.

Abstract

The aim of this study was to compare the prevalence of EBV genotype and del-LMP-1 in saliva from Polish, Taiwanese and Arabic healthy students. The study group consisted of 56 healthy students; 24 of them Polish, 25 Taiwanese, and 7 Arabic. Typing was carried out using PCR with EBNA-2 primers. A detection of LMP-1 variants was also performed using PCR. EBV DNA was detected in 22 investigated samples (39.3%). Type 1 of the virus was dominant in both Polish and Taiwanese group. Among 62.5% Taiwanese with EBV 1 and 55.6% Polish detected EBV with 30-bp deletion in LMP-1 gene.

MeSH terms

  • Adolescent
  • Adult
  • Carrier State / virology
  • Female
  • Gene Expression Regulation, Viral / physiology
  • Genetic Variation
  • Genotype*
  • Herpesvirus 4, Human / genetics*
  • Herpesvirus 4, Human / isolation & purification
  • Humans
  • Male
  • Phylogeny*
  • Poland
  • Saudi Arabia
  • Taiwan
  • Viral Matrix Proteins / genetics
  • Viral Matrix Proteins / metabolism*
  • Young Adult

Substances

  • EBV-associated membrane antigen, Epstein-Barr virus
  • Viral Matrix Proteins