Abstract
beta-Lapachone, an antimicrobial agent, markedly increase the generation of H2O2 in intact Trypanosoma cruzi epimastigotes (Y strain). Increase in H2O2 was determined by the horseradish peroxidase-H2O2 Compound II formation as well as by a cytochemical technique.
MeSH terms
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3,3'-Diaminobenzidine / pharmacology
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Anti-Bacterial Agents / pharmacology*
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Hydrogen Peroxide / biosynthesis*
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Trypanosoma cruzi / metabolism*
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Trypanosoma cruzi / ultrastructure
Substances
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Anti-Bacterial Agents
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3,3'-Diaminobenzidine
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Hydrogen Peroxide