Microwave-assisted Cu(I)-catalyzed, three-component synthesis of 2-(4-((1-phenyl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-1H-benzo[d]imidazoles

Yogesh Kumar; Vijay Bahadur; Anil Kumar Singh; Virinder Singh Parmar; Erik V Van der Eycken; Brajendra Kumar Singh

doi:10.3762/bjoc.10.145

Microwave-assisted Cu(I)-catalyzed, three-component synthesis of 2-(4-((1-phenyl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-1H-benzo[d]imidazoles

Beilstein J Org Chem. 2014 Jun 24:10:1413-20. doi: 10.3762/bjoc.10.145. eCollection 2014.

Authors

Yogesh Kumar¹, Vijay Bahadur¹, Anil Kumar Singh¹, Virinder Singh Parmar¹, Erik V Van der Eycken², Brajendra Kumar Singh¹

Affiliations

¹ Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi 110 007, India.
² Laboratory for Organic & Microwave-Assisted Chemistry (LOMAC), Department of Chemistry, University of Leuven (KU Leuven), Celestijnenlaan 200F, B-3001 Leuven, Belgium.

Abstract

A microwave-assisted synthesis of 2-(4-((1-phenyl-1H-1,2,3-triazol-4-yl)methoxy)phenyl)-1H-benzo[d]imidazoles from a phenylazide, propargyloxybenzaldehyde and a 1,2-diaminobenzene is proposed.

Keywords: Cu(I) catalysis; benzimidazole; microwave-assisted synthesis; multicomponent; three component synthesis.