Disseminated histoplasmosis in allogeneic bone marrow transplant: a diagnosis not to be missed

Transpl Infect Dis. 2014 Oct;16(5):822-6. doi: 10.1111/tid.12261. Epub 2014 Jul 1.

Abstract

Immunosuppressed patients are at highest risk for disseminated histoplasmosis, but only a few cases have been reported in hematopoietic stem cell transplant recipients. We report a case of disseminated histoplasmosis in an allogeneic bone marrow transplant recipient residing in a non-endemic area. Diagnosis was first suspected based on a peripheral blood smear.

Keywords: Histoplasma capsulatum; allogeneic bone marrow transplant; disseminated histoplasmosis; peripheral blood smear.

Publication types

  • Case Reports

MeSH terms

  • Bone Marrow Transplantation / adverse effects*
  • Brain Diseases / cerebrospinal fluid
  • Brain Diseases / microbiology*
  • Fatal Outcome
  • Histoplasmosis / diagnosis*
  • Histoplasmosis / immunology
  • Humans
  • Immunocompromised Host / immunology*
  • Lung Diseases, Fungal / diagnostic imaging
  • Lung Diseases, Fungal / microbiology*
  • Lymphoma, Mantle-Cell / therapy
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Radiography