Distal posterior inferior cerebellar artery aneurysms: clinical features and outcome of 80 patients

World Neurosurg. 2014 Nov;82(5):702-13. doi: 10.1016/j.wneu.2014.06.012. Epub 2014 Jun 14.

Abstract

Objective: Aneurysms of the posterior inferior cerebellar artery (PICA) distal to its origin are rare. Beside their rarity, their treatment is challenged by a high proportion of fusiform aneurysms, torturous course of PICA, and often severe bleeding. Our aim is to represent the characteristics of these aneurysms and their treatment, as well as to analyze outcome.

Methods: We reviewed retrospectively 80 patients with PICA aneurysms who were treated at the Department of Neurosurgery, Helsinki, Finland.

Results: The 80 patients had altogether 91 distal PICA aneurysms. Subarachnoid hemorrhage occurred in 74 (93%), and the distal PICA aneurysm was ruptured in 68 (85%). Compared with aneurysms at other locations, distal PICA aneurysms were smaller, more often fusiform, and more often caused an intraventricular hemorrhage as well as rebleeding. Modified surgical techniques (trapping, wrapping, proximal occlusion, resection, coagulation) were used in 10 (32%) fusiform and in 3 (6%) saccular aneurysms. Revascularization was needed in 3 (4%) cases. One aneurysm was primarily embolized. Within a year after aneurysm diagnosis, 18 patients had died. Among survivors, most returned to independent or previous state of living: 52 (91%); only 1 patient was unable to return home.

Conclusions: Microsurgery is a feasible treatment for distal PICA aneurysms. Despite the challenge of often severe hemorrhage, wide-necked aneurysms, and some risk for laryngeal palsy, most patients surviving the initial stage return to normal life. Because of the greater number of rebleedings than for aneurysms at other locations, immediate treatment is crucial.

Keywords: Cerebral aneurysm; Microsurgery; Posterior inferior cerebellar artery; Vertebral artery.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aneurysm, Ruptured / mortality
  • Aneurysm, Ruptured / surgery*
  • Cerebellum / blood supply
  • Cerebral Revascularization / methods*
  • Cerebral Revascularization / mortality
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Intracranial Arteriovenous Malformations / mortality
  • Intracranial Arteriovenous Malformations / surgery
  • Male
  • Microsurgery / methods*
  • Microsurgery / mortality
  • Middle Aged
  • Prognosis
  • Recovery of Function
  • Retrospective Studies
  • Subarachnoid Hemorrhage / mortality
  • Subarachnoid Hemorrhage / surgery*
  • Treatment Outcome
  • Vertebral Artery / abnormalities
  • Vertebral Artery / surgery
  • Young Adult