Cereblon expression predicts clinical response in chronic lymphocytic leukemia treated with a thalidomide/fludarabine regimen

MeSH terms

• Adaptor Proteins, Signal Transducing
• Adult
• Aged
• Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
• Disease-Free Survival
• Female
• Gene Expression Regulation, Leukemic / drug effects*
• Humans
• Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy*
• Leukemia, Lymphocytic, Chronic, B-Cell / genetics*
• Leukemia, Lymphocytic, Chronic, B-Cell / pathology
• Logistic Models
• Male
• Middle Aged
• Multivariate Analysis
• Peptide Hydrolases / genetics*
• Pilot Projects
• Predictive Value of Tests
• Prognosis
• Reverse Transcriptase Polymerase Chain Reaction
• Thalidomide / administration & dosage
• Treatment Outcome
• Ubiquitin-Protein Ligases
• Vidarabine / administration & dosage
• Vidarabine / analogs & derivatives