Tumor thrombus in the renal vein from an adrenal metastasis of lung cancer: 18FDG PET/CT findings

Cancer Biother Radiopharm. 2014 Jun;29(5):189-92. doi: 10.1089/cbr.2014.1612. Epub 2014 May 22.

Abstract

Tumor thrombus is a rare complication of solid cancer. The authors report a case of a 76-year-old woman presenting a thick walled cystic mass in the lower lobe of the left lung. 18FDG positron emission tomography (PET)/computed tomography (CT) was performed, showing tracer accumulation in the wall of the pulmonary lesion and in the mediastinal and hilar lymph nodes. Moreover, PET/CT depicted a gross mass in the left adrenal gland and a hypermetabolic focus corresponding to the anatomic location of the left renal vein. Contrast-enhanced CT, subsequently performed, confirmed PET findings in the lung, lymph nodes, and adrenal glands, also demonstrating marginal enhancement and intraluminal filling defect in the left renal vein, which was interpreted as tumor thrombus due to the 18FDG uptake at PET scan. CT-guided biopsy of the mass was positive for poorly differentiated carcinoma. 18FDG PET can be useful to diagnose tumor thrombus in oncological patients.

Keywords: 18FDG PET; adrenal gland; lung cancer; tumor thrombus.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Gland Neoplasms / diagnostic imaging*
  • Adrenal Gland Neoplasms / pathology
  • Adrenal Gland Neoplasms / secondary*
  • Aged
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / pathology
  • Multimodal Imaging / methods
  • Neoplasm Metastasis
  • Positron-Emission Tomography / methods
  • Radiopharmaceuticals
  • Renal Veins / diagnostic imaging*
  • Renal Veins / pathology
  • Tomography, X-Ray Computed / methods
  • Venous Thromboembolism / diagnostic imaging*
  • Venous Thromboembolism / pathology

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18