Refeeding syndrome is uncommon in alcoholics admitted to a hospital detoxification unit

Intern Med J. 2014 May;44(5):512-4. doi: 10.1111/imj.12408.

Abstract

The refeeding syndrome is increasingly recognised. It is a serious change in electrolytes when nutrition is reintroduced to malnourished patients. Alcohol dependence is a risk factor for the refeeding syndrome. We report a prospective cohort study of 36 alcoholics hospitalised for withdrawal management. We found no evidence of refeeding syndrome in any patient after 3 days of hospitalisation, despite hypomagnesaemia, a risk factor for the refeeding syndrome being prevalent (44% of subjects). Low thiamine levels were infrequent affecting 3/29 (10%). We recommend that in alcoholics admitted for managed withdrawal, risk of refeeding syndrome appears to be low, and routine testing of repeat electrolytes appears unnecessary.

Keywords: alcohol dependence; detoxification; hypophosphataemia; refeeding syndrome.

MeSH terms

  • Adult
  • Aged
  • Alcoholism / complications
  • Alcoholism / rehabilitation*
  • Blood Chemical Analysis / statistics & numerical data
  • Diagnostic Tests, Routine / statistics & numerical data
  • Diet
  • Electrolytes / blood
  • Female
  • Hospital Units*
  • Humans
  • Male
  • Malnutrition / blood
  • Malnutrition / diet therapy
  • Malnutrition / etiology
  • Middle Aged
  • Patient Admission
  • Prevalence
  • Prospective Studies
  • Refeeding Syndrome / blood
  • Refeeding Syndrome / epidemiology*
  • Refeeding Syndrome / etiology
  • Thiamine / blood
  • Thiamine / therapeutic use
  • Thiamine Deficiency / drug therapy
  • Thiamine Deficiency / epidemiology
  • Thiamine Deficiency / etiology
  • Unnecessary Procedures
  • Victoria / epidemiology
  • Young Adult

Substances

  • Electrolytes
  • Thiamine