Tic-TACs: refreshing hair growth

Demetrios Kalaitzidis; David T Scadden

doi:10.1016/j.cell.2014.04.014

Tic-TACs: refreshing hair growth

Cell. 2014 May 8;157(4):769-70. doi: 10.1016/j.cell.2014.04.014.

Authors

Demetrios Kalaitzidis¹, David T Scadden²

Affiliations

¹ Center for Regenerative Medicine, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Harvard Stem Cell Institute and Harvard University Department of Stem Cell and Regenerative Biology, 7 Divinity Avenue, Cambridge, MA 02138, USA. Electronic address: dkalaitzidis@partners.org.
² Center for Regenerative Medicine, Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA; Harvard Stem Cell Institute and Harvard University Department of Stem Cell and Regenerative Biology, 7 Divinity Avenue, Cambridge, MA 02138, USA. Electronic address: david_scadden@harvard.edu.

Abstract

Although stem cells are subject to niche control, evidence is emerging that they also contribute to generating the niche through their offspring. Using the hair follicle as a model, Hsu at al. demonstrate that the transient-amplifying cells, downstream of stem cells and well-known cell producers, signal back to stem cells to maintain long-term regenerative capacity.

Publication types

Comment

MeSH terms

Animals
Hair / cytology*
Hair / physiology*
Hair Follicle / cytology*
Stem Cell Niche*
Stem Cells / cytology*

Abstract

Publication types

MeSH terms

Grants and funding