Peak oxygen uptake test in the assessment of growth hormone deficiency

Appl Physiol Nutr Metab. 2014 Jul;39(7):852-5. doi: 10.1139/apnm-2013-0483. Epub 2014 Feb 19.

Abstract

This study aimed at evaluating a peak oxygen uptake test as a simple diagnostic tool to assess growth-hormone deficiency (GHD) in adults. Based on the findings of multiple growth hormone (GH) samplings after the exercise, a single GH sample taken 15 min postexercise revealed high accuracy in the diagnosis of GHD in the present study. A standardized peak oxygen uptake test may, therefore, provide an accurate alternative to more invasive tests of GHD.

Keywords: V̇O2peak test; analyse de fonction d’efficacité du récepteur (FER); diagnostic accuracy; diagnostic test; déficience en hormone de croissance; growth hormone deficiency; growth hormone secretion; précision du diagnostic; receiver operating characteristics (ROC) analysis; sécrétion de l’hormone de croissance; test diagnostique; test du V̇O2 de pointe.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Case-Control Studies
  • Deficiency Diseases / diagnosis
  • Deficiency Diseases / metabolism
  • Human Growth Hormone / deficiency*
  • Humans
  • Male
  • Middle Aged
  • Oxygen / metabolism*
  • Prospective Studies

Substances

  • Human Growth Hormone
  • Oxygen