Incisional surgical site infection after elective open surgery for colorectal cancer

Int J Surg Oncol. 2014:2014:419712. doi: 10.1155/2014/419712. Epub 2014 Mar 27.

Abstract

Background: The purpose of this study was to clarify the incidence and risk factors for incisional surgical site infections (SSI) in patients undergoing elective open surgery for colorectal cancer.

Methods: We conducted prospective surveillance of incisional SSI after elective colorectal resections performed by a single surgeon for a 1-year period. Variables associated with infection, as identified in the literature, were collected and statistically analyzed for their association with incisional SSI development.

Results: A total of 224 patients were identified for evaluation. The mean patient age was 67 years, and 120 (55%) were male. Thirty-three (14.7%) patients were diagnosed with incisional SSI. Multivariate analysis suggested that incisional SSI was independently associated with TNM stages III and IV (odds ratio [OR], 2.4) and intraoperative hypotension (OR, 3.4).

Conclusions: The incidence of incisional SSI in our cohort was well within values generally reported in the literature. Our data suggest the importance of the maintenance of intraoperative normotension to reduce the development of incisional SSI.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Antibiotic Prophylaxis
  • Colorectal Neoplasms / surgery*
  • Elective Surgical Procedures / adverse effects
  • Female
  • Humans
  • Length of Stay / statistics & numerical data
  • Male
  • Methicillin-Resistant Staphylococcus aureus
  • Middle Aged
  • Prospective Studies
  • Pseudomonas Infections / etiology*
  • Pseudomonas aeruginosa
  • Risk Factors
  • Staphylococcal Infections / etiology*
  • Staphylococcus epidermidis
  • Surgical Wound Infection / etiology*