The combination of ribavirin and ozeltamivir effectively inhibits reproduction of influenza A virus resistant to rimantadine (amantadine) in vitro and in vivo

MeSH terms

• Amantadine / pharmacology
• Animals
• Antiviral Agents / administration & dosage
• Antiviral Agents / pharmacology*
• Antiviral Agents / therapeutic use
• Dogs
• Drug Combinations
• Drug Resistance, Viral
• Influenza A virus / drug effects*
• Influenza A virus / physiology
• Madin Darby Canine Kidney Cells
• Mice
• Orthomyxoviridae Infections / drug therapy*
• Oseltamivir / administration & dosage
• Oseltamivir / pharmacology*
• Oseltamivir / therapeutic use
• Ribavirin / administration & dosage
• Ribavirin / pharmacology*
• Ribavirin / therapeutic use
• Virus Replication / drug effects*