Takotsubo's syndrome after mitral valve repair and rescue with extracorporeal membrane oxygenation

Ann Thorac Surg. 2014 May;97(5):1777-8. doi: 10.1016/j.athoracsur.2013.08.032.

Abstract

We report a case of Takotsubo's syndrome in a 37-year-old woman after mitral valve repair for severe mitral regurgitation triggered by a severe protamine reaction that was likely associated with immune-mediated coronary hypersensitivity (Kounis' syndrome) and made worse by resuscitation with high doses of catecholamines. The patient recovered fully after a 4-day course of extracorporeal membrane oxygenation therapy (ECMO).

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Cardiopulmonary Resuscitation / methods
  • Critical Illness
  • Drug-Related Side Effects and Adverse Reactions / etiology
  • Drug-Related Side Effects and Adverse Reactions / therapy
  • Echocardiography, Doppler / methods
  • Extracorporeal Membrane Oxygenation / methods*
  • Female
  • Follow-Up Studies
  • Heart Valve Prosthesis Implantation / adverse effects*
  • Heart Valve Prosthesis Implantation / methods
  • Humans
  • Mitral Valve Insufficiency / diagnostic imaging
  • Mitral Valve Insufficiency / surgery*
  • Mitral Valve Prolapse / diagnostic imaging
  • Mitral Valve Prolapse / surgery
  • Postoperative Complications / physiopathology
  • Postoperative Complications / therapy
  • Protamines / administration & dosage
  • Protamines / adverse effects*
  • Risk Assessment
  • Severity of Illness Index
  • Takotsubo Cardiomyopathy / etiology
  • Takotsubo Cardiomyopathy / therapy*
  • Treatment Outcome

Substances

  • Protamines