Rhinovirus and the developing lung

D W Cox; P N Le Souëf

doi:10.1016/j.prrv.2014.03.002

Rhinovirus and the developing lung

Paediatr Respir Rev. 2014 Sep;15(3):268-74. doi: 10.1016/j.prrv.2014.03.002. Epub 2014 Mar 27.

Authors

D W Cox¹, P N Le Souëf²

Affiliations

¹ School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia; Respiratory Department, Our Lady's Children's Hospital, Crumlin, Dublin 12, Ireland.
² School of Paediatrics and Child Health, University of Western Australia, Perth, WA, Australia; Respiratory Medicine, Princess Margaret Hospital for Children, Perth, WA, Australia.

PMID: 24767866
DOI: 10.1016/j.prrv.2014.03.002

Abstract

Human rhinovirus (HRV) infections are now widely accepted as the commonest cause of acute respiratory illnesses (ARIs) in children. Advanced PCR techniques have enabled HRV infections to be identified as causative agents in most common ARIs in childhood including bronchiolitis, acute asthma, pneumonia and croup. However, the long-term implications of rhinovirus infections are less clear. The aim of this review is to examine the relationship between rhinovirus infections and disorders of the lower airways in childhood.

Keywords: Rhinovirus; children; respiratory illnesses.

Publication types

Review

MeSH terms

Bronchiolitis / physiopathology
Child
Child, Preschool
Common Cold / complications*
Common Cold / physiopathology*
Humans
Infant
Lung / growth & development*
Phenotype
Rhinovirus* / classification
Rhinovirus* / genetics