Possible leap ahead in filovirus therapeutics

Cell Res. 2014 Jun;24(6):647-8. doi: 10.1038/cr.2014.49. Epub 2014 Apr 15.

Abstract

In a recent study published in Nature, Warren et al. describe the generation of a novel synthetic adenosine analogue, BCX4430, a synthetic drug-like small molecule that provides protection from Ebola and Marburg virus infection in animal models.

Publication types

  • Comment

MeSH terms

  • Adenosine / analogs & derivatives*
  • Animals
  • Antiviral Agents / pharmacology*
  • Filoviridae / drug effects*
  • Filoviridae Infections / prevention & control*
  • Filoviridae Infections / virology*
  • Humans
  • Purine Nucleosides / pharmacology*

Substances

  • Antiviral Agents
  • Purine Nucleosides
  • Adenosine