Perforation of enteric duplication during chemotherapy for osteosarcoma

Pediatr Int. 2014 Apr;56(2):279-82. doi: 10.1111/ped.12251.

Abstract

A 9-year-old boy undergoing chemotherapy for conventional osteosarcoma complained of severe abdominal pain associated with rebound tenderness and muscular defense. Abdominal computed tomography indicated intraperitoneal free air. On surgical investigation, a diverticulum-like lesion, perforated at the base, was found on the sidewall of the ileum. The anatomic location of the lesion was indicative of enteric duplication. Although the frequency of complications is very rare, perforations of the digestive tract should be considered in patients suffering severe abdominal pain while receiving chemotherapy.

Keywords: chemotherapy; enteric duplication; gastrointestinal disturbance; osteosarcoma; perforation.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Bone Neoplasms / complications*
  • Bone Neoplasms / drug therapy*
  • Child
  • Humans
  • Ileal Diseases / chemically induced*
  • Intestinal Perforation / chemically induced*
  • Intestines / abnormalities*
  • Male
  • Osteosarcoma / complications*
  • Osteosarcoma / drug therapy*
  • Tibia*

Substances

  • Antineoplastic Agents