Diagnostic methods for and clinical pictures of polyomavirus primary infections in children, Finland

Emerg Infect Dis. 2014 Apr;20(4):689-92. doi: 10.3201/eid2004.131015.

Abstract

We used comprehensive serodiagnostic methods (IgM, IgG, and IgG avidity) and PCR to study Merkel cell polyomavirus and trichodysplasia spinulosa-associated polyomavirus infections in children observed from infancy to adolescence. Comparing seroconversion intervals with previous and subsequent intervals, we found that primary infections with these 2 viruses were asymptomatic in childhood.

Keywords: Finland; Merkel cell polyomavirus; childhood; primary infection; serodiagnostics; trichodysplasia spinulosa-associated polyomavirus; viruses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Finland
  • Humans
  • Immunoglobulins / immunology
  • Infant
  • Infant, Newborn
  • Merkel cell polyomavirus / immunology
  • Merkel cell polyomavirus / isolation & purification*
  • Polyomavirus / immunology
  • Polyomavirus / isolation & purification*
  • Polyomavirus Infections / diagnosis*
  • Polyomavirus Infections / immunology
  • Prospective Studies
  • Retrospective Studies
  • Tumor Virus Infections / diagnosis*
  • Tumor Virus Infections / immunology

Substances

  • Immunoglobulins