Engineering self-sufficient aldehyde deformylating oxygenases fused to alternative electron transfer systems for efficient conversion of aldehydes into alkanes

Chem Commun (Camb). 2014 Apr 28;50(33):4299-301. doi: 10.1039/c4cc00591k.

Abstract

Self-sufficient aldehyde deformylating oxygenases (ADOs) from Synechococcus elongatus PCC7942 fused to alternative electron transfer systems were successfully designed, constructed, characterized and used for efficient conversion of aldehydes into alkanes for the first time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehydes / chemistry
  • Aldehydes / metabolism*
  • Alkanes / chemistry
  • Alkanes / metabolism*
  • Bacterial Proteins / chemistry
  • Bacterial Proteins / metabolism*
  • Electron Transport
  • Electrons
  • Kinetics
  • Oxygenases / chemistry
  • Oxygenases / metabolism*
  • Protein Engineering
  • Synechococcus / enzymology

Substances

  • Aldehydes
  • Alkanes
  • Bacterial Proteins
  • Oxygenases