Endovascular treatment of symptomatic high-grade vertebral artery stenosis

J Vasc Surg. 2014 Jul;60(1):92-7. doi: 10.1016/j.jvs.2014.01.023. Epub 2014 Feb 21.

Abstract

Background: The purpose of this study was to evaluate the initial and long-term results of endovascular treatment (EVT) in patients with symptomatic high-grade extracranial vertebral artery (VA) origin stenosis.

Methods: From February 2001 to March 2013, 73 consecutive patients (33 men with a mean age of 61.7 ± 8.8 years) underwent EVT for symptomatic high-grade VA stenosis. Preoperative evaluation included Duplex ultrasonography and arteriography. After successful treatment, all patients were followed up at 1, 3, 6, and 12 months after the procedure and every 6 months thereafter.

Results: Successful EVT of the VA stenosis was achieved in 68 patients (93.2%). All procedures were performed without use of cerebral protection. The early complication rate was 5.5%, which included one periprocedural transient ischemic attack, two hematomas at the puncture site, and one allergic reaction to the contrast agent. No in-hospital deaths occurred. During follow-up (mean, 44.3 ± 31.2 months; range, 2-144 months), the primary patency rates at 1, 3, 5, and 7 years were 98.4%, 87.3%, 87.3%, and 87.3%, respectively. Ultrasound Doppler controls during follow-up detected seven VA restenoses (10.3%). Univariate analysis failed to identify any variable predictive of long-term patency of successfully treated VA stenosis.

Conclusions: EVT of symptomatic VA origin stenosis is a safe and effective procedure associated with low risk and good long-term results, even without use of cerebral protection devices.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Angioplasty* / adverse effects
  • Contrast Media / adverse effects
  • Drug Hypersensitivity / etiology
  • Female
  • Follow-Up Studies
  • Hematoma / etiology
  • Humans
  • Ischemic Attack, Transient / etiology
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Recurrence
  • Retrospective Studies
  • Stents
  • Treatment Outcome
  • Ultrasonography, Doppler, Color
  • Vascular Patency
  • Vertebrobasilar Insufficiency / complications
  • Vertebrobasilar Insufficiency / diagnosis
  • Vertebrobasilar Insufficiency / surgery*

Substances

  • Contrast Media