Unexpected course of Beckmann rearrangement of taraxerone oxime with Ac₂O/AcOH

Nat Prod Res. 2014;28(8):568-72. doi: 10.1080/14786419.2013.879584. Epub 2014 Feb 19.

Abstract

The chemistry of pentacyclic taraxerane-type triterpenoids has not been extensively studied. In the course of our synthesis of nitrogen-containing heterocyclic compounds from taraxerone using Beckmann rearrangement with Ac2O/AcOH as the rearrangement agent, unexpected synthetic pathways were discovered leading to new types of modified taraxerane skeletons.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Electron Spin Resonance Spectroscopy
  • Euphorbiaceae / chemistry*
  • Molecular Structure
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / chemistry
  • Oximes / chemistry*

Substances

  • Oximes
  • Oleanolic Acid
  • taraxerone