Schwannomas are common, truly encapsulated and benign peripheral nerve sheath tumors. Their occurrence in extracranial locations is rare. Schwannomas most commonly occur in adults between 20 and 50 years of age. Their symptomatology usually mimics sciatic pain due to herniated disc. The most common clinical presentation of sciatic nerve schwannoma is a painful palpable mass. A 40-year-old woman was admitted to our neurosurgery department with a slow-growing mass at the medial right posterior thigh. Magnetic resonance imaging (MRI) showed a mass involving the right sciatic nerve in its middle portion. No neurological deficit was noted postoperatively. The result of the histopathological examination was reported as schwannoma. We report a case of large sciatic schwannoma with chronic sciatica.