Atrial fibrillation as manifestation and consequence of underlying cardiomyopathies: from common conditions to genetic diseases

Heart Fail Rev. 2014 May;19(3):295-304. doi: 10.1007/s10741-014-9424-0.

Abstract

While atrial fibrillation is common comorbidity in patients with cardiomyopathy and heart failure, diagnosis and management often focuses on tackling rate and rhythm control rather than elucidating pathogenic mechanisms related to underlying myocardial substrates. This review summarizes our current understanding of the natural history of cardiomyopathies presenting with atrial fibrillation, and the importance of managing underlying cardiomyopathic condition as diagnostic and treatment strategy for atrial fibrillation.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Anti-Arrhythmia Agents / therapeutic use*
  • Atrial Fibrillation* / drug therapy
  • Atrial Fibrillation* / etiology
  • Atrial Fibrillation* / physiopathology
  • Atrial Remodeling*
  • Cardiomyopathies* / classification
  • Cardiomyopathies* / complications
  • Cardiomyopathies* / diagnosis
  • Cardiomyopathies* / genetics
  • Cardiomyopathies* / physiopathology
  • Cardiomyopathies* / therapy
  • Disease Management
  • Genome-Wide Association Study
  • Heart Failure / etiology
  • Heart Failure / physiopathology
  • Heart Function Tests / methods
  • Heart Rate
  • Humans
  • Mutation*

Substances

  • Anti-Arrhythmia Agents