High levels of interferon in synovial fluid of retrovirus-infected goats

T Yilma; S Owens; D S Adams

doi:10.1089/jir.1988.8.45

High levels of interferon in synovial fluid of retrovirus-infected goats

J Interferon Res. 1988 Feb;8(1):45-50. doi: 10.1089/jir.1988.8.45.

Authors

T Yilma¹, S Owens, D S Adams

Affiliation

¹ Department of Veterinary Microbiology and Immunology, University of California, Davis 95616.

PMID: 2452849
DOI: 10.1089/jir.1988.8.45

Abstract

A high level of interferon (IFN) was found in the synovial fluid of goats with naturally acquired caprine arthritis-encephalitis (CAE), a disease caused by caprine arthritis-encephalitis virus (CAEV), a nononcogenic retrovirus of the lentivirus group. Intraarticular injection of CAEV or control inoculum in the joints of affected goats caused increased amounts of IFN production in synovial fluid.

Publication types

Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Animals
Arthritis / physiopathology
Arthritis / veterinary*
Goats*
Interferons / analysis*
Retroviridae
Retroviridae Infections / physiopathology*
Synovial Fluid / analysis*
Time Factors

Substances

Interferons