Assessing the impact of public health interventions on the transmission of pandemic H1N1 influenza a virus aboard a Peruvian navy ship

Influenza Other Respir Viruses. 2014 May;8(3):353-9. doi: 10.1111/irv.12240. Epub 2014 Feb 10.

Abstract

Background: Limited data exist on transmission dynamics and effectiveness of control measures for influenza in confined settings.

Objectives: To investigate the transmission dynamics of a 2009 pandemic H1N1 influenza A outbreak aboard a Peruvian Navy ship and quantify the effectiveness of the implemented control measures.

Methods: We used surveillance data and a simple stochastic epidemic model to characterize and evaluate the effectiveness of control interventions implemented during an outbreak of 2009 pandemic H1N1 influenza A aboard a Peruvian Navy ship.

Results: The serological attack rate for the outbreak was 49·1%, with younger cadets and low-ranking officers at greater risk of infection than older, higher-ranking officers. Our transmission model yielded a good fit to the daily time series of new influenza cases by date of symptom onset. We estimated a reduction of 54·4% in the reproduction number during the period of intense control interventions.

Conclusion: Our results indicate that the patient isolation strategy and other control measures put in place during the outbreak reduced the infectiousness of isolated individuals by 86·7%. Our findings support that early implementation of control interventions can limit the spread of influenza epidemics in confined settings.

Keywords: Disease outbreak; Peru; influenza; military personnel; ships; transmission.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Humans
  • Influenza A Virus, H1N1 Subtype / isolation & purification
  • Influenza A Virus, H1N1 Subtype / physiology
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control*
  • Influenza, Human / transmission*
  • Influenza, Human / virology
  • Male
  • Middle Aged
  • Military Personnel / statistics & numerical data
  • Public Health
  • Ships / statistics & numerical data
  • Young Adult