Comparable sensitivities for detection of human immunodeficiency virus by sensitive reverse transcriptase and antigen capture enzyme-linked immunosorbent assays

J Clin Microbiol. 1988 Feb;26(2):371-4. doi: 10.1128/jcm.26.2.371-374.1988.

Abstract

The sensitive overnight reverse transcriptase and the antigen capture enzyme-linked immunosorbent assays were tested for their ability to detect human immunodeficiency virus. The two assays were able to quantitate as few as 75 to 130 virus particles. Thus, both tests offer similar sensitivities for determining the presence of the virus.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Antibodies, Viral / immunology
  • Antigens, Viral / analysis*
  • Cell Line
  • Enzyme-Linked Immunosorbent Assay*
  • HIV / enzymology
  • HIV / immunology
  • HIV / isolation & purification*
  • HIV Antibodies
  • HIV Antigens
  • Humans
  • Predictive Value of Tests
  • RNA-Directed DNA Polymerase / analysis*
  • Reagent Kits, Diagnostic

Substances

  • Antibodies, Viral
  • Antigens, Viral
  • HIV Antibodies
  • HIV Antigens
  • Reagent Kits, Diagnostic
  • RNA-Directed DNA Polymerase