Controlled release from magnetoliposomes aqueous suspensions exposed to a low intensity magnetic field

Bioelectromagnetics. 2014 May;35(4):309-12. doi: 10.1002/bem.21841. Epub 2014 Jan 31.

Abstract

Recently, the use of liposomes loaded with magnetic nanoparticles (magnetoliposomes, (MLs)) has been intensely growing as a new drug delivery system. With the use of alternating magnetic fields, it is possible to remotely control the delivery of a drug or any other macromolecule loaded inside the MLs. In this experiment, the release of a fluorescent dye from MLs is achieved through an alternating magnetic field of 20 kHz and amplitude below 100 A/m, and without a macroscopic temperature increase.

Keywords: IF magnetic field; drug delivery; liposomes; magnetic nanoparticle; stimuli-responsive carriers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Delayed-Action Preparations
  • Drug Delivery Systems
  • Liposomes*
  • Magnetic Fields*
  • Metal Nanoparticles / administration & dosage*
  • Pilot Projects
  • Temperature

Substances

  • Delayed-Action Preparations
  • Liposomes