Scale-up of malaria rapid diagnostic tests and artemisinin-based combination therapy: challenges and perspectives in sub-Saharan Africa

Guido J H Bastiaens; Teun Bousema; Toby Leslie

doi:10.1371/journal.pmed.1001590

Scale-up of malaria rapid diagnostic tests and artemisinin-based combination therapy: challenges and perspectives in sub-Saharan Africa

PLoS Med. 2014 Jan;11(1):e1001590. doi: 10.1371/journal.pmed.1001590. Epub 2014 Jan 21.

Authors

Guido J H Bastiaens¹, Teun Bousema², Toby Leslie³

Affiliations

¹ Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
² Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands ; Department of Immunology and Infection, London School of Hygiene & Tropical Medicine, London, United Kingdom.
³ Department of Disease Control, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Abstract

Guido Bastiaens and colleagues describe barriers to achieving scale-up and appropriate use of rapid diagnostic tests and artemisinin-based combination therapy for malaria in sub-Saharan Africa.

Please see later in the article for the Editors' Summary

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Africa South of the Sahara
Antimalarials / therapeutic use*
Artemisinins / therapeutic use*
Delivery of Health Care
Diagnostic Tests, Routine / statistics & numerical data*
Drug Combinations
Health Knowledge, Attitudes, Practice
Health Policy
Humans
Malaria / diagnosis*
Malaria / drug therapy*
Malaria / parasitology

Substances

Antimalarials
Artemisinins
Drug Combinations
artemisinin

Grants and funding

Guido Bastiaens is a PhD student employed at the Radboud University Medical Center. Teun Bousema is supported through a grant from the Bill & Melinda Gates Foundation, 51991. Toby Leslie is supported by the ACT Consortium with a grant from the Bill & Melinda Gates Foundation through the London School of Hygiene & Tropical Medicine, 39640. The funders had no role in design, analysis, decision to publish, or preparation of the manuscript.