Management of Scedosporium apiospermum in a pre- and post-lung transplant patient with cystic fibrosis

Nancy E Rolfe; Tarik J Haddad; Todd S Wills

doi:10.1016/j.mmcr.2013.01.002

Management of Scedosporium apiospermum in a pre- and post-lung transplant patient with cystic fibrosis

Med Mycol Case Rep. 2013 Jan 24:2:37-9. doi: 10.1016/j.mmcr.2013.01.002.

Authors

Nancy E Rolfe¹, Tarik J Haddad², Todd S Wills¹

Affiliations

¹ University of South Florida Morsani College of Medicine, Department of Infectious Diseases and International Medicine, Tampa, FL, US.
² New Lung Associates Transplant and Adult Cystic Fibrosis Center, Tampa, FL, US.

Abstract

Although the predominant type of infection seen in the cystic fibrosis lung remains bacterial, fungal organisms are being isolated more frequently and are associated with a high mortality rate in lung transplant recipients. We present a case of a patient with CF with sputum cultures positive for Scedosporium apiospermum prior to a successful lung transplant. She remains without evidence of infection 18 months later following treatment with a combination of triazoles and terbinafine.

Keywords: Cystic fibrosis; Lung transplantation; Scedosporium; Voriconazole.