Immunological homogeneity of Lafora body, corpora amylacea, basophilic degeneration in heart, and intracytoplasmic inclusions of liver and heart in type IV glycogenosis

Acta Pathol Jpn. 1987 Jun;37(6):941-6. doi: 10.1111/j.1440-1827.1987.tb00443.x.

Abstract

Antisera against Lafora bodies were made in rabbits by subcutaneous injection of the myocardium from a patient died of Lafora disease. Using this antisera, immunohistochemistry revealed that corpora amylacea, the basophilic degeneration of myocardium and deposits of type IV glycogenosis contained the materials which were antigenically common to Lafora bodies.

MeSH terms

  • Amyloid / analysis*
  • Epilepsies, Myoclonic / immunology*
  • Epilepsies, Myoclonic / pathology
  • Glycogen Storage Disease / immunology*
  • Glycogen Storage Disease Type IV / immunology*
  • Glycogen Storage Disease Type IV / pathology
  • Histocytochemistry
  • Humans
  • Immune Sera / immunology
  • Inclusion Bodies / immunology*
  • Liver / ultrastructure*
  • Myocardium / pathology*
  • Myocardium / ultrastructure
  • Staining and Labeling

Substances

  • Amyloid
  • Immune Sera