[The obsessive compulsive disorder]

Med Sci (Paris). 2013 Dec;29(12):1111-6. doi: 10.1051/medsci/20132912014. Epub 2013 Dec 20.
[Article in French]

Abstract

The obsessive compulsive disorder (OCD) is a frequent disease with a high comorbidity. The usual treatment is a combination of pharmacological and psychotherapeutic treatment. However, 30% of patients still have persistent and severe symptoms, with an important functional impact. These last years, the integration of the new neuroanatomical, neurochemical, neuropsychological, genetic and phenomenological data, allows a better understanding of the physiopathology and the development of new treatments for OCD, as neuromodulation for the severe and refractory cases.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Combined Modality Therapy
  • Comorbidity
  • Deep Brain Stimulation
  • Excitatory Amino Acid Antagonists / therapeutic use
  • Genetic Diseases, Inborn
  • Humans
  • Neurotransmitter Agents
  • Obsessive-Compulsive Disorder* / epidemiology
  • Obsessive-Compulsive Disorder* / etiology
  • Obsessive-Compulsive Disorder* / therapy
  • Psychotherapy

Substances

  • Excitatory Amino Acid Antagonists
  • Neurotransmitter Agents