Developmental endothelial locus-1 attenuates complement-dependent phagocytosis through inhibition of Mac-1-integrin

Thromb Haemost. 2014 May 5;111(5):1004-6. doi: 10.1160/TH13-09-0794. Epub 2013 Dec 19.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Blocking / pharmacology
  • CD11b Antigen / genetics
  • CD11b Antigen / immunology
  • CD11c Antigen / immunology
  • CHO Cells
  • Calcium-Binding Proteins
  • Carrier Proteins / metabolism*
  • Cell Adhesion / drug effects
  • Cell Adhesion / genetics
  • Cell Adhesion Molecules
  • Complement C3b / metabolism
  • Cricetulus
  • Endothelial Cells / physiology*
  • Intercellular Adhesion Molecule-1 / metabolism
  • Intercellular Signaling Peptides and Proteins
  • Leukocytes / immunology
  • Leukocytes / metabolism*
  • Lymphocyte Function-Associated Antigen-1 / metabolism
  • Macrophage-1 Antigen / genetics
  • Macrophage-1 Antigen / metabolism*
  • Macrophages / drug effects
  • Macrophages / physiology*
  • Mice
  • Mice, Knockout
  • Phagocytosis
  • Protein Binding / drug effects
  • Protein Binding / genetics
  • Transgenes / genetics

Substances

  • Antibodies, Blocking
  • CD11b Antigen
  • CD11c Antigen
  • Calcium-Binding Proteins
  • Carrier Proteins
  • Cell Adhesion Molecules
  • Edil3 protein, mouse
  • Intercellular Signaling Peptides and Proteins
  • Lymphocyte Function-Associated Antigen-1
  • Macrophage-1 Antigen
  • Intercellular Adhesion Molecule-1
  • Complement C3b