Failure of malaria chemoprophylaxis with mefloquine in an oversize traveller to Mozambique

Malar J. 2013 Dec 18:12:451. doi: 10.1186/1475-2875-12-451.

Abstract

A case of failure of mefloquine prophylaxis in an oversize traveller, who correctly took the drug. This case seems to be attributed to mefloquine resistance, however it is suggested that mefloquine dosage should be modulated by body weight, as is already indicated by some authorities.

Publication types

  • Case Reports

MeSH terms

  • Antimalarials / therapeutic use*
  • Chemoprevention / methods*
  • Drug Resistance
  • Humans
  • Malaria / prevention & control*
  • Male
  • Mefloquine / therapeutic use*
  • Middle Aged
  • Mozambique
  • Plasmodium falciparum / drug effects
  • Plasmodium falciparum / isolation & purification
  • Travel*
  • Treatment Failure

Substances

  • Antimalarials
  • Mefloquine