Use of Cox regression with treatment status as a time-dependent covariate to re-analyze survival benefit excludes immortal time bias effect in patients with glioblastoma who received prolonged adjuvant treatment with valganciclovir

Int J Cancer. 2014 Jul 1;135(1):248-9. doi: 10.1002/ijc.28663. Epub 2014 Jan 6.

Authors

Cecilia Söderberg-Naucler¹, Inti Peredo, Afsar Rahbar, Fredrik Hansson, Anders Nordlund, Giuseppe Stragliotto

Affiliation

¹ Department of Medicine Solna Unit for Experimental Medicine Cell and Molecular Immunology, Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.

PMID: 24338548
DOI: 10.1002/ijc.28663

No abstract available

Publication types

Letter
Comment

MeSH terms

Antiviral Agents / therapeutic use*
Brain Neoplasms / virology*
Cytomegalovirus / drug effects*
Female
Ganciclovir / analogs & derivatives*
Glioblastoma / virology*
Humans
Male

Substances

Antiviral Agents
Ganciclovir