1 Swiss Institute of Bioinformatics, Geneva, Switzerland, Lawrence Berkeley National Laboratory, USA, University of Lausanne, Switzerland, Faculty of Life Sciences and School of Computer Science, The University of Manchester, UK, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, UK, Department of Genetics, Stanford University, Stanford, CA, USA, Heidelberg Institute for Theoretical Studies, Heidelberg, Germany and National Institute of Biomedical Innovation (NIBIO), Osaka, Japan.