Schizophillum commune causing sinusitis with nasal polyposis in the sub-Himalayan region: first case report and review

Mycopathologia. 2014 Feb;177(1-2):103-10. doi: 10.1007/s11046-013-9717-1. Epub 2013 Dec 7.

Abstract

Schizophillum commune is an environmental fungus rarely causing human infections of diverse nature. Sinusitis occurs in immunocompromised persons and seldom in healthy subjects. Though easily isolated, the lack of awareness of its virulence is a bottleneck in the diagnosis of this infection. We report the first case of S. commune sinusitis with nasal polyps in an immunocompetent male from the sub-Himalayan region. The computerized tomography scan findings established the clinical diagnosis, and causative agent was confirmed as S. commune. A white, woolly mold with septate, hyaline hyphae and characteristic spicules but unclamped connections suggested a monokaryotic isolate. Patient was treated successfully with fiberoptic endoscopic sinus surgery, and no antifungal therapy was instituted. There was no recurrence at review after 1 year.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Aged
  • Endoscopy
  • Female
  • Humans
  • Hyphae / physiology
  • Male
  • Middle Aged
  • Mycological Typing Techniques
  • Mycoses / diagnosis
  • Mycoses / microbiology*
  • Mycoses / surgery
  • Nasal Polyps / microbiology*
  • Nasal Polyps / surgery
  • Schizophyllum / pathogenicity*
  • Sinusitis / diagnosis
  • Sinusitis / microbiology*
  • Sinusitis / surgery
  • Tomography, X-Ray Computed
  • Young Adult