Rituximab in the treatment of shrinking lung syndrome in systemic lupus erythematosus

Abstract

Shrinking lung syndrome (SLS) is a rare manifestation of systemic lupus erythematosus. We report the case of a patient with non-responding SLS (neither to glucocorticoids nor immunosupresors), who showed remarkable improvement after the onset of treatment with rituximab. Although there is a little evidence, treatment with rituximab could be proposed in SLS when classical treatment fails.

Keywords: Glucocorticoides; Glucocorticoids; Lupus eritematoso sistémico; Rituximab; Shrinking lung syndrome; Systemic lupus erythematosus; Síndrome del pulmón encogido.